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Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance
Brian M. Barth
, Sally J. Gustafson
,
Megan M. Young
, Todd E. Fox
, Sriram S. Shanmugavelandy
, James M. Kaiser
, Myles C. Cabot
, Mark Kester
, Thomas B. Kuhn
Department of Cell and Biological Systems
Research output
:
Contribution to journal
›
Article
›
peer-review
28
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Scopus citations
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Keyphrases
Chemoresistance
100%
NADPH Oxidase
100%
Oxidative Stress
40%
Resistance Mechanisms
40%
Malignant Cells
40%
NADPH Oxidase Activity
40%
Delivery System
20%
Tumor Necrosis Factor-α
20%
Ceramide
20%
Reactive Oxygen Species Production
20%
Paclitaxel
20%
Nanoliposomes
20%
Mitochondrial Function
20%
Molecular Targets
20%
Glioblastoma
20%
Glioblastoma Cells
20%
Neuroblastoma Cells
20%
Bioactive Sphingolipids
20%
Vinca Alkaloids
20%
Cell Death Pathways
20%
Anthracyclines
20%
Fenretinide
20%
Sphingolipid Ceramide
20%
Pharmacological Targeting
20%
Physiological Stimuli
20%
Biochemistry, Genetics and Molecular Biology
Drug Resistance
100%
NAD(P)H Oxidase
100%
Ceramide Glucosyltransferase
100%
Ceramide
60%
Oxidative Stress
40%
Metabolic Pathway
20%
Cell Death
20%
Tumor Necrosis Factor
20%
Nanoliposome
20%
Anticancer
20%
Upregulation
20%
Sphingolipid
20%
Vinca
20%
Anthracycline
20%
Pharmacology, Toxicology and Pharmaceutical Science
Drug Resistance
100%
Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase
100%
Ceramide Glucosyltransferase
100%
Ceramide
60%
Glioblastoma
40%
Tumor Necrosis Factor
20%
Sphingolipid
20%
Paclitaxel
20%
Neuroblastoma
20%
Reactive Oxygen Metabolite
20%
Vinca Alkaloid
20%
Fenretinide
20%
Anthracycline
20%
Neuroscience
Anthracycline
20%
Vinca Alkaloid
20%