Inhibition of vascular endothelial growth factor expression and production by triptolide

Kebin Hu; Zhi Hong Liu; Dong Liu; Lei Shi Li

doi:10.1055/s-2002-26737

Inhibition of vascular endothelial growth factor expression and production by triptolide

Kebin Hu, Zhi Hong Liu, Dong Liu, Lei Shi Li

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Triptolide, the major component of the diterpenoids of the Chinese herb Tripterygium wilfordii Hook f. (Celastraceae), inhibited vascular endothelial growth factor expression and secretion in endothelial cells treated by 12-O-tetradecanoylphorbol 13-acetate dose-dependently. This effect may be one of the mechanisms underlying the therapeutic effects of triptolide on rheumatoid arthritis.

Original language	English (US)
Pages (from-to)	368-369
Number of pages	2
Journal	Planta Medica
Volume	68
Issue number	4
DOIs	https://doi.org/10.1055/s-2002-26737
State	Published - 2002

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1055/s-2002-26737

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title = "Inhibition of vascular endothelial growth factor expression and production by triptolide",

abstract = "Triptolide, the major component of the diterpenoids of the Chinese herb Tripterygium wilfordii Hook f. (Celastraceae), inhibited vascular endothelial growth factor expression and secretion in endothelial cells treated by 12-O-tetradecanoylphorbol 13-acetate dose-dependently. This effect may be one of the mechanisms underlying the therapeutic effects of triptolide on rheumatoid arthritis.",

author = "Kebin Hu and Liu, {Zhi Hong} and Dong Liu and Li, {Lei Shi}",

year = "2002",

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AU - Hu, Kebin

AU - Liu, Zhi Hong

AU - Liu, Dong

AU - Li, Lei Shi

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AB - Triptolide, the major component of the diterpenoids of the Chinese herb Tripterygium wilfordii Hook f. (Celastraceae), inhibited vascular endothelial growth factor expression and secretion in endothelial cells treated by 12-O-tetradecanoylphorbol 13-acetate dose-dependently. This effect may be one of the mechanisms underlying the therapeutic effects of triptolide on rheumatoid arthritis.

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JO - Planta Medica

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ER -

Inhibition of vascular endothelial growth factor expression and production by triptolide

Abstract

All Science Journal Classification (ASJC) codes

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