Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections

Robert J. Woods; Twisha S. Patel; Jerod L. Nagel; Duane W. Newton; Andrew F. Read

doi:10.1017/ice.2017.279

Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections

Robert J. Woods, Twisha S. Patel, Jerod L. Nagel, Duane W. Newton, Andrew F. Read

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We report daptomycin minimum inhibitory concentrations (MICs) for vancomycin-resistant Enterococcus faecium isolated from bloodstream infections over a 4-year period. The daptomycin MIC increased over time hospital-wide for initial isolates and increased over time within patients, culminating in 40% of patients having daptomycin-nonsusceptible isolates in the final year of the study.

Original language	English (US)
Pages (from-to)	226-228
Number of pages	3
Journal	Infection Control and Hospital Epidemiology
Volume	39
Issue number	2
DOIs	https://doi.org/10.1017/ice.2017.279
State	Published - Feb 1 2018

All Science Journal Classification (ASJC) codes

Epidemiology
Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1017/ice.2017.279

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abstract = "We report daptomycin minimum inhibitory concentrations (MICs) for vancomycin-resistant Enterococcus faecium isolated from bloodstream infections over a 4-year period. The daptomycin MIC increased over time hospital-wide for initial isolates and increased over time within patients, culminating in 40% of patients having daptomycin-nonsusceptible isolates in the final year of the study.",

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AU - Newton, Duane W.

AU - Read, Andrew F.

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AB - We report daptomycin minimum inhibitory concentrations (MICs) for vancomycin-resistant Enterococcus faecium isolated from bloodstream infections over a 4-year period. The daptomycin MIC increased over time hospital-wide for initial isolates and increased over time within patients, culminating in 40% of patients having daptomycin-nonsusceptible isolates in the final year of the study.

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Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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