Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections

Robert J. Woods, Twisha S. Patel, Jerod L. Nagel, Duane W. Newton, Andrew F. Read

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

We report daptomycin minimum inhibitory concentrations (MICs) for vancomycin-resistant Enterococcus faecium isolated from bloodstream infections over a 4-year period. The daptomycin MIC increased over time hospital-wide for initial isolates and increased over time within patients, culminating in 40% of patients having daptomycin-nonsusceptible isolates in the final year of the study.

Original languageEnglish (US)
Pages (from-to)226-228
Number of pages3
JournalInfection Control and Hospital Epidemiology
Volume39
Issue number2
DOIs
StatePublished - Feb 1 2018

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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