Intensive care management of closed head injury

W. Andrew Kofke

Research output: Contribution to journalReview articlepeer-review


Maintenance of nutritive cerebral perfusion is the essence of providing care to the patient with neurosurgical disease. Many neurosurgical problems include elements of intracranial hypertension. The dual nature of cerebral perfusion with elevated ICP, oligemic versus hyperemic, can lead to disparate therapeutic strategies. These issues and others with conflicting therapeutic priorities are discussed in this chapter.

Original languageEnglish (US)
Pages (from-to)322-339
Number of pages18
JournalProblems in Anesthesia
Issue number3
StatePublished - 2001

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine


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