TY - JOUR
T1 - Inter-membrane control of junctional InsP3 receptors by PIP2
AU - Zhou, Yandong
AU - Wang, Youjun
AU - Gill, Donald L.
N1 - Publisher Copyright:
© 2024 Elsevier Ltd
PY - 2025/1
Y1 - 2025/1
N2 - Crosstalk between junctional membrane proteins is vital in the coordinated generation of cellular Ca2+ signals. New evidence (Ivanova et al.) reveals the signaling lipid, phosphatidylinositol 4,5-bisphosphate (PIP2) reaches across plasma membrane (PM)–endoplasmic reticulum (ER) junctions to regulate inositol 1,4,5-trisphosphate receptors, controlling the critical progression of local to global Ca2+ signals mediating a spectrum of fundamental cellular responses.
AB - Crosstalk between junctional membrane proteins is vital in the coordinated generation of cellular Ca2+ signals. New evidence (Ivanova et al.) reveals the signaling lipid, phosphatidylinositol 4,5-bisphosphate (PIP2) reaches across plasma membrane (PM)–endoplasmic reticulum (ER) junctions to regulate inositol 1,4,5-trisphosphate receptors, controlling the critical progression of local to global Ca2+ signals mediating a spectrum of fundamental cellular responses.
UR - http://www.scopus.com/inward/record.url?scp=85210544191&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85210544191&partnerID=8YFLogxK
U2 - 10.1016/j.tcb.2024.11.004
DO - 10.1016/j.tcb.2024.11.004
M3 - Short survey
C2 - 39613531
AN - SCOPUS:85210544191
SN - 0962-8924
VL - 35
SP - 1
EP - 3
JO - Trends in Cell Biology
JF - Trends in Cell Biology
IS - 1
ER -