TY - JOUR
T1 - Intestinal fat suppressed intake of fat longer than intestinal sucrose
AU - Foster, L. A.
AU - Boeshore, K.
AU - Norgren, R.
N1 - Funding Information:
This research was supported by Public Health Service Grants DC 00067 and DC00240. R. Norgren is a recipient of an National Institute of Mental Health (NIMH) Research Scientist Award (MH 00653)
PY - 1998/6/15
Y1 - 1998/6/15
N2 - Although animals eventually stop eating when only experiencing the oro-sensory stimuli from a food, they stop eating much more rapidly if they also receive postgastric stimuli simultaneously. This suggests that the postgastric effects of a nutrient influence the hedonic value of food or motivation to consume that food, and thus, can influence food selection within the time frame of a meal. In this experiment, rats were equipped with a gastric fistula and duodenal cannula. This combination allowed them to receive the same oro-sensory stimuli, but different postgastric nutrients. While ingesting either a fat (Intralipid) or carbohydrate (sucrose) solution, both of which drained from the gastric fistula, the rats received a duodenal infusion of either sucrose (10 mLs, 0.24 kcals/mL), fat (10 mLs, 0.25 kcals/mL) or saline (10 mLs, 0 kcals/mL). While ingesting the Intralipid, a duodenal infusion of fat suppressed intake quicker and longer than an infusion of sucrose. While the animals ingested sucrose, sucrose and fat suppressed intake equivalently. Copyright (C) 1998 Elsevier Science Inc.
AB - Although animals eventually stop eating when only experiencing the oro-sensory stimuli from a food, they stop eating much more rapidly if they also receive postgastric stimuli simultaneously. This suggests that the postgastric effects of a nutrient influence the hedonic value of food or motivation to consume that food, and thus, can influence food selection within the time frame of a meal. In this experiment, rats were equipped with a gastric fistula and duodenal cannula. This combination allowed them to receive the same oro-sensory stimuli, but different postgastric nutrients. While ingesting either a fat (Intralipid) or carbohydrate (sucrose) solution, both of which drained from the gastric fistula, the rats received a duodenal infusion of either sucrose (10 mLs, 0.24 kcals/mL), fat (10 mLs, 0.25 kcals/mL) or saline (10 mLs, 0 kcals/mL). While ingesting the Intralipid, a duodenal infusion of fat suppressed intake quicker and longer than an infusion of sucrose. While the animals ingested sucrose, sucrose and fat suppressed intake equivalently. Copyright (C) 1998 Elsevier Science Inc.
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U2 - 10.1016/S0031-9384(98)00053-5
DO - 10.1016/S0031-9384(98)00053-5
M3 - Article
C2 - 9761218
AN - SCOPUS:0031669815
SN - 0031-9384
VL - 64
SP - 451
EP - 455
JO - Physiology and Behavior
JF - Physiology and Behavior
IS - 4
ER -