Intracerebroventricular enterostatin stimulates food intake in non-food-deprived rats

Harry Benjamin Rice, Rebecca L. Corwin

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Previous studies reported that ICV enterostatin reduced high-fat food intake in food-deprived rats. The present study sought to determine if ICV enterostatin would decrease intake of a high-fat food in non-food-deprived rats. Eight doses (0-32 μg) were tested. Enterostatin (32 μg) significantly stimulated cookie intake at 30 min. Enterostatin did not reduce food intake at any dose. These results conflict with previous reports and suggest that central enterostatin does not play a role in suppressing, but may play a role in stimulating, high-fat food consumption in non-food-deprived rats.

Original languageEnglish (US)
Pages (from-to)885-888
Number of pages4
JournalPeptides
Volume17
Issue number5
DOIs
StatePublished - Jan 1 1996

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physiology
  • Endocrinology
  • Cellular and Molecular Neuroscience

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