TY - JOUR
T1 - Intraoperative Assessment of Acute Hemodynamic Changes After Partial Left Ventriculectomy
AU - Koenig, Steven
AU - Shafie, Mohammad
AU - Pearson, Anthony
AU - Laureano, Mary Ann
AU - Cerrito, Pat
AU - Ewert, Daniel
AU - Schroeder, Mark
AU - Dowling, Robert D.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1985/3
Y1 - 1985/3
N2 - Abstract Partial left ventriculectomy (PLV) has been introduced as an alternative surgical therapy for patients with end‐stage dilated cardiomyopathy. The physiological benefits of PLV are relatively unknown. Therefore, the objective of this study was to determine the acute effects of PLV by measuring cardiac function before and after PLV. Aortic and left ventricular pressures and aortic flow were measured in eight patients. Continuous, beat‐to‐beat data were recorded and compared pre‐PLV and post‐PLV with and without inferior vena cava (IVC) occlusions. PLV increased cardiac output (0.93 ± 0.5, p = 0.01) as a result of increased stroke volume (5.12 ± 4.24, p = 0.06) and heart rate (14.5 ± 8.44, p = 0.02). Contractility (± dP/dt, 240.33 ± 74.28, p = 0.001) and external work (650.8 ± 320.4, p = 0.01) were also improved. Left ventricular end‐diastolic elastance (0.15 ± 0.14, p = 0.10) nearly doubled after PLV. Our results indicated an improved cardiac function as measured by increased cardiac output, stroke volume, ejection fraction (EF), and contractility.
AB - Abstract Partial left ventriculectomy (PLV) has been introduced as an alternative surgical therapy for patients with end‐stage dilated cardiomyopathy. The physiological benefits of PLV are relatively unknown. Therefore, the objective of this study was to determine the acute effects of PLV by measuring cardiac function before and after PLV. Aortic and left ventricular pressures and aortic flow were measured in eight patients. Continuous, beat‐to‐beat data were recorded and compared pre‐PLV and post‐PLV with and without inferior vena cava (IVC) occlusions. PLV increased cardiac output (0.93 ± 0.5, p = 0.01) as a result of increased stroke volume (5.12 ± 4.24, p = 0.06) and heart rate (14.5 ± 8.44, p = 0.02). Contractility (± dP/dt, 240.33 ± 74.28, p = 0.001) and external work (650.8 ± 320.4, p = 0.01) were also improved. Left ventricular end‐diastolic elastance (0.15 ± 0.14, p = 0.10) nearly doubled after PLV. Our results indicated an improved cardiac function as measured by increased cardiac output, stroke volume, ejection fraction (EF), and contractility.
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U2 - 10.1111/j.1540-8175.1985.tb01265.x
DO - 10.1111/j.1540-8175.1985.tb01265.x
M3 - Article
AN - SCOPUS:85005233603
SN - 0742-2822
VL - 2
SP - 152
EP - 156
JO - Echocardiography
JF - Echocardiography
IS - 2
ER -