TY - JOUR
T1 - Intraoperative radiotherapy in the multimodality approach to bone and soft tissue cancers
AU - Ellis, Rodney J.
AU - Kim, Edward
AU - Kinsella, Timothy J.
AU - Eisenberg, Burton L.
PY - 2003/10
Y1 - 2003/10
N2 - IORT is a powerful tool for the management of cancer and has been shown to improve local control in the treatment of sarcomas in one prospective, randomized, controlled trial. IORT allows dose escalation in areas where escalation with EBRT would cause potentially excessive acute or late normal tissue toxicity. It has a unique toxicity profile but remains safe and effective when used in appropriately selected patients. In addition, IORT is becoming more widely available at different cancer centers and offers great flexibility in treatment planning for a wide variety of malignancies. As IORT use becomes more common, special care will be required to ensure that it is used by a multidisciplinary team of radiation oncologists and surgeons to ensure the best results for patients.
AB - IORT is a powerful tool for the management of cancer and has been shown to improve local control in the treatment of sarcomas in one prospective, randomized, controlled trial. IORT allows dose escalation in areas where escalation with EBRT would cause potentially excessive acute or late normal tissue toxicity. It has a unique toxicity profile but remains safe and effective when used in appropriately selected patients. In addition, IORT is becoming more widely available at different cancer centers and offers great flexibility in treatment planning for a wide variety of malignancies. As IORT use becomes more common, special care will be required to ensure that it is used by a multidisciplinary team of radiation oncologists and surgeons to ensure the best results for patients.
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U2 - 10.1016/S1055-3207(03)00095-4
DO - 10.1016/S1055-3207(03)00095-4
M3 - Review article
C2 - 14989130
AN - SCOPUS:0345449062
SN - 1055-3207
VL - 12
SP - 1015
EP - 1029
JO - Surgical Oncology Clinics of North America
JF - Surgical Oncology Clinics of North America
IS - 4
ER -