TY - JOUR
T1 - Intrapartum fever, epidural analgesia and histologic chorioamnionitis
AU - Curtin, W. M.
AU - Katzman, P. J.
AU - Florescue, H.
AU - Metlay, L. A.
AU - Ural, S. H.
N1 - Publisher Copyright:
© 2015 Nature America, Inc. All rights reserved.
PY - 2015/6/28
Y1 - 2015/6/28
N2 - OBJECTIVE:Our objective was to determine whether epidural analgesia and histologic chorioamnionitis were independent predictors of intrapartum fever.Study Design:This secondary analysis, retrospective cohort study included term parturients with placental examination during 2005. Logistic regression used fever (≥38 °C) as the dependent variable. Significance was defined as P≤0.05.Result:There were 488 (76%) of 641 term parturients with placental examination and epidural. Independent predictors of intrapartum fever were epidural odds ratio (OR)=3.4, confidence interval (CI): 1.70, 6.81, histologic chorioamnionitis OR=3.18, 95% CI: 2.04, 4.95, birthweight OR=2.07, 95%CI: 1.38, 3.12, vaginal exams OR=1.15, 95% CI:1.06, 1.24, duration ruptured membranes OR=1.03, 95% CI: 1.01,1.05, parity≥1 OR=0.44: 0.29, 0.66 and thick meconium OR=0.35: 95%CI: 0.24, 0.85.Conclusion:Epidural analgesia and histologic chorioamnionitis were independent predictors of intrapartum fever. Modification of labor management may reduce the incidence of intrapartum fever.
AB - OBJECTIVE:Our objective was to determine whether epidural analgesia and histologic chorioamnionitis were independent predictors of intrapartum fever.Study Design:This secondary analysis, retrospective cohort study included term parturients with placental examination during 2005. Logistic regression used fever (≥38 °C) as the dependent variable. Significance was defined as P≤0.05.Result:There were 488 (76%) of 641 term parturients with placental examination and epidural. Independent predictors of intrapartum fever were epidural odds ratio (OR)=3.4, confidence interval (CI): 1.70, 6.81, histologic chorioamnionitis OR=3.18, 95% CI: 2.04, 4.95, birthweight OR=2.07, 95%CI: 1.38, 3.12, vaginal exams OR=1.15, 95% CI:1.06, 1.24, duration ruptured membranes OR=1.03, 95% CI: 1.01,1.05, parity≥1 OR=0.44: 0.29, 0.66 and thick meconium OR=0.35: 95%CI: 0.24, 0.85.Conclusion:Epidural analgesia and histologic chorioamnionitis were independent predictors of intrapartum fever. Modification of labor management may reduce the incidence of intrapartum fever.
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U2 - 10.1038/jp.2014.235
DO - 10.1038/jp.2014.235
M3 - Article
C2 - 25675051
AN - SCOPUS:84929951277
SN - 0743-8346
VL - 35
SP - 396
EP - 400
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 6
ER -