Intravenous nutrition in uremic children with protein-energy malnutrition

M. A. Holliday, S. Wassner, J. Ramirez

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The use of intravenous nutrition therapy in children and young adults who have renal failure is a practical means for improving nutritional state. Optimum use of this therapy depends upon: knowledge of the differences in body composition at different ages and the effect these have upon energy and protein requirements; the nutritional-metabolic status of the patient and the relation of energy intake to projected rates of recovery from protein-energy-malnutrition and knowledge of the physiological limitations renal failure imposes upon fluid and substrate administration. The ideal protein: energy ratio, and the preferred composition of the amino acid mixture, are not yet defined. Our studies indicate that an essential amino acids formulation in a ratio of 1 g/100 kcal delivered, or a general amino acids formulation of 2 g/100 kcal, will induce retention of nitrogen as body protein. When there are signs of protein deficiency more protein may be given with less energy intake, however, giving less energy may be a factor that impairs efficiency in protein use.

Original languageEnglish (US)
Pages (from-to)1854-1860
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Issue number10
StatePublished - 1978

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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