Investigation of the stereochemistry of intermolecular conjugate additions of nucleophiles to acyclic nitrosoalkenes

Jason A. Witek, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Michael-type conjugate additions of γ-chiral aldehyde-derived acyclic nitrosoalkenes have been explored using a series of carbon and hetero nucleophiles. In all cases examined, these reactions are stereoselective, leading exclusively to the anti products.(Figure Presented)

Original languageEnglish (US)
Pages (from-to)1258-1260
Number of pages3
JournalOrganic Letters
Volume13
Issue number5
DOIs
StatePublished - Mar 4 2011

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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