Investigative Landscape in Advanced Non-Melanoma Skin Cancers

Priyanka Reddy, Min Yao, Monaliben Patel

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Advanced non-melanoma skin cancers have been challenging to treat due to limited treatment options. Treatment paradigm has shifted with the approval of immunotherapeutic agents cemiplimab and pembrolizumab which have been a key development and have changed the landscape of advanced or metastatic squamous cell skin cancers. Hedgehog inhibitors, vismodegib and sonidegib, remain upfront options for advanced or metastatic basal cell carcinomas. Current clinical trials are continuing to evaluate the use of immune checkpoint inhibitors and hedgehog pathway inhibitors. There is further need for ongoing research and development of new therapies in both malignancies.

Original languageEnglish (US)
Article number56
JournalCurrent treatment options in oncology
Issue number7
StatePublished - Jul 2021

All Science Journal Classification (ASJC) codes

  • Oncology
  • Pharmacology (medical)


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