J147 Reduces tPA-Induced Brain Hemorrhage in Acute Experimental Stroke in Rats

Keyphrases

• Tissue Plasminogen Activator (t-PA) 100%
• Experimental Stroke 100%
• Brain Hemorrhage 100%
• J147 100%
• Transient Middle Cerebral Artery Occlusion (tMCAO) 36%
• Combination Treatment 27%
• Vascular Thrombosis 18%
• Acute Ischemic Stroke 18%
• Infarct Volume 18%
• Stroke Onset 18%
• Cerebroprotective Effect 18%
• Combination Therapy 9%
• Aging 9%
• Protective Effect 9%
• Neutrophils 9%
• Occlusion 9%
• Intracerebral Hemorrhage 9%
• Neurological Diseases 9%
• Matrix metalloproteinase-9 (MMP-9) 9%
• Platelet Activation 9%
• Microglial Activation 9%
• Neurological Deficit 9%
• Middle Cerebral Artery 9%
• Ischemic Stroke 9%
• Neuroinflammation 9%
• Plasminogen Activator inhibitor-1 (PAI-1) 9%
• Platelet-leukocyte Aggregates 9%
• Neurotrophic Agents 9%
• Thrombolytic Therapy 9%
• Embolic Stroke 9%
• 15-lipoxygenase (15-LOX) 9%
• Circulating Platelets 9%
• Volume Deficit 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Tissue Plasminogen Activator 100%
• Brain Hemorrhage 100%
• Experimental Stroke 100%
• Cerebrovascular Accident 45%
• Brain Ischemia 27%
• Middle Cerebral Artery Occlusion 27%
• Infarction 18%
• Cytoprotective Agent 18%
• Thrombosis 18%
• Table Salt 18%
• Suture 18%
• Combination Therapy 9%
• Gelatinase B 9%
• Neurologic Disease 9%
• Nervous System Inflammation 9%
• Fibrinolytic Agent 9%
• Plasminogen Activator Inhibitor 9%
• Arachidonate 15 Lipoxygenase 9%

Neuroscience

• Tissue Plasminogen Activator 100%
• Cerebral Hemorrhage 100%
• Cerebrovascular Accident 100%
• Middle Cerebral Artery 36%
• Brain Ischemia 27%
• Platelet 18%
• Nervous System Disorder 9%
• MMP9 9%
• Thrombolytic Drug 9%
• Arachidonate 15 Lipoxygenase 9%
• Plasminogen Activator Inhibitor 9%
• Embolic Stroke 9%