J147 treatment protects against traumatic brain injury by inhibiting neuronal endoplasmic reticulum stress potentially via the AMPK/SREBP-1 pathway

Keyphrases

• Traumatic Brain Injury 100%
• Sterol Regulatory Element-binding protein-1c (SREBP-1c) 100%
• Endoplasmic Reticulum Stress (ER stress) 100%
• AMP-activated Protein Kinase 100%
• J147 100%
• Dephosphorylation 33%
• Functional Recovery 33%
• Oral Administration 16%
• Signaling Pathway 16%
• Neuroplasticity 16%
• Neuropathology 16%
• EIF2 16%
• Neurodegeneration 16%
• Behavioral Assessment 16%
• Neurological Recovery 16%
• Adult Mice 16%
• Marker Proteins 16%
• Controlled Cortical Impact 16%
• Activating Transcription Factor 4 (ATF4) 16%
• Perilesional 16%
• Neuron Survival 16%
• Neurotrophic Agents 16%
• EIF2a 16%
• Secondary Brain Damage 16%
• C/EBP Homologous Protein 16%
• Dose-dependent 16%
• Therapeutic Interventions 16%
• Daily Dosing 16%
• Cortex Cells 16%
• Endoplasmic Reticulum Stress Pathway 16%

Neuroscience

• Neurotrauma 100%
• Traumatic Brain Injury 100%
• Endoplasmic Reticulum Stress 100%
• AMP-activated Protein Kinase 100%
• Sterol Regulatory Element Binding Protein 1 100%
• Staining Technique 50%
• Dephosphorylation 33%
• Cell Signaling 16%
• Prothrombin 16%
• Neurodegeneration 16%
• Neuroplasticity 16%
• Activating Transcription Factor 4 16%