Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Fulvio Gala; Maria Valeria D'Auria; Simona De Marino; Valentina Sepe; Franco Zollo; Charles D. Smith; Staci N. Keller; Angela Zampella

doi:10.1016/j.tet.2008.10.076

Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Fulvio Gala, Maria Valeria D'Auria, Simona De Marino, Valentina Sepe, Franco Zollo, Charles D. Smith, Staci N. Keller, Angela Zampella

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.

Original language	English (US)
Pages (from-to)	51-56
Number of pages	6
Journal	Tetrahedron
Volume	65
Issue number	1
DOIs	https://doi.org/10.1016/j.tet.2008.10.076
State	Published - Jan 3 2009

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2008.10.076

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title = "Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans",

abstract = "Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.",

author = "Fulvio Gala and D'Auria, {Maria Valeria} and {De Marino}, Simona and Valentina Sepe and Franco Zollo and Smith, {Charles D.} and Keller, {Staci N.} and Angela Zampella",

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T2 - new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

AU - Gala, Fulvio

AU - D'Auria, Maria Valeria

AU - De Marino, Simona

AU - Sepe, Valentina

AU - Zollo, Franco

AU - Smith, Charles D.

AU - Keller, Staci N.

AU - Zampella, Angela

PY - 2009/1/3

Y1 - 2009/1/3

N2 - Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.

AB - Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.

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M3 - Article

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SP - 51

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JO - Tetrahedron

JF - Tetrahedron

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Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Abstract

All Science Journal Classification (ASJC) codes

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