Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Fulvio Gala; Maria Valeria D'Auria; Simona De Marino; Valentina Sepe; Franco Zollo; Charles D. Smith; Staci N. Keller; Angela Zampella

doi:10.1016/j.tet.2008.10.076

Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Fulvio Gala
, Maria Valeria D'Auria
, Simona De Marino
, Valentina Sepe
, Franco Zollo
, Charles D. Smith
, Staci N. Keller
, Angela Zampella

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.

Original language	English (US)
Pages (from-to)	51-56
Number of pages	6
Journal	Tetrahedron
Volume	65
Issue number	1
DOIs	https://doi.org/10.1016/j.tet.2008.10.076
State	Published - Jan 3 2009

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2008.10.076

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title = "Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans",

abstract = "Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.",

author = "Fulvio Gala and D'Auria, \{Maria Valeria\} and \{De Marino\}, Simona and Valentina Sepe and Franco Zollo and Smith, \{Charles D.\} and Keller, \{Staci N.\} and Angela Zampella",

year = "2009",

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doi = "10.1016/j.tet.2008.10.076",

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T2 - new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

AU - Gala, Fulvio

AU - D'Auria, Maria Valeria

AU - De Marino, Simona

AU - Sepe, Valentina

AU - Zollo, Franco

AU - Smith, Charles D.

AU - Keller, Staci N.

AU - Zampella, Angela

PY - 2009/1/3

Y1 - 2009/1/3

N2 - Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.

AB - Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.

UR - https://www.scopus.com/pages/publications/56949095877

UR - https://www.scopus.com/pages/publications/56949095877#tab=citedBy

U2 - 10.1016/j.tet.2008.10.076

DO - 10.1016/j.tet.2008.10.076

M3 - Article

AN - SCOPUS:56949095877

SN - 0040-4020

VL - 65

SP - 51

EP - 56

JO - Tetrahedron

JF - Tetrahedron

IS - 1

ER -

Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Abstract

All Science Journal Classification (ASJC) codes

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