Keratoacanthoma-Like Growths of Incontinentia Pigmenti Successfully Treated with Intralesional Methotrexate

Brittany Barros; Klaus Helm; Andrea Zaenglein; Elizabeth Seiverling

doi:10.1111/pde.13142

Keratoacanthoma-Like Growths of Incontinentia Pigmenti Successfully Treated with Intralesional Methotrexate

Brittany Barros, Klaus Helm, Andrea Zaenglein, Elizabeth Seiverling

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4 Scopus citations

Abstract

We report the case of a 17-year-old girl with incontinentia pigmenti who developed multiple large hyperkeratotic tumors within Blaschkoid hyperpigmented patches on her left leg. Biopsy demonstrated an endoexophytic nodule with irregular invaginations of keratinizing squamous epithelium and a central keratin-filled crater, consistent with keratoacanthoma-like lesions of incontinentia pigmenti. The tumors were successfully treated with intralesional methotrexate.

Original language	English (US)
Pages (from-to)	e203-e204
Journal	Pediatric dermatology
Volume	34
Issue number	4
DOIs	https://doi.org/10.1111/pde.13142
State	Published - Jul 1 2017

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Dermatology

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10.1111/pde.13142

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title = "Keratoacanthoma-Like Growths of Incontinentia Pigmenti Successfully Treated with Intralesional Methotrexate",

abstract = "We report the case of a 17-year-old girl with incontinentia pigmenti who developed multiple large hyperkeratotic tumors within Blaschkoid hyperpigmented patches on her left leg. Biopsy demonstrated an endoexophytic nodule with irregular invaginations of keratinizing squamous epithelium and a central keratin-filled crater, consistent with keratoacanthoma-like lesions of incontinentia pigmenti. The tumors were successfully treated with intralesional methotrexate.",

author = "Brittany Barros and Klaus Helm and Andrea Zaenglein and Elizabeth Seiverling",

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T1 - Keratoacanthoma-Like Growths of Incontinentia Pigmenti Successfully Treated with Intralesional Methotrexate

AU - Barros, Brittany

AU - Helm, Klaus

AU - Zaenglein, Andrea

AU - Seiverling, Elizabeth

PY - 2017/7/1

Y1 - 2017/7/1

N2 - We report the case of a 17-year-old girl with incontinentia pigmenti who developed multiple large hyperkeratotic tumors within Blaschkoid hyperpigmented patches on her left leg. Biopsy demonstrated an endoexophytic nodule with irregular invaginations of keratinizing squamous epithelium and a central keratin-filled crater, consistent with keratoacanthoma-like lesions of incontinentia pigmenti. The tumors were successfully treated with intralesional methotrexate.

AB - We report the case of a 17-year-old girl with incontinentia pigmenti who developed multiple large hyperkeratotic tumors within Blaschkoid hyperpigmented patches on her left leg. Biopsy demonstrated an endoexophytic nodule with irregular invaginations of keratinizing squamous epithelium and a central keratin-filled crater, consistent with keratoacanthoma-like lesions of incontinentia pigmenti. The tumors were successfully treated with intralesional methotrexate.

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Keratoacanthoma-Like Growths of Incontinentia Pigmenti Successfully Treated with Intralesional Methotrexate

Abstract

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