Abstract
Acute kidney injury (AKI) occurs frequently in patients with liver disease and increases morbidity and mortality. Hepatorenal syndrome is a common cause of AKI in patients with decompensated cirrhosis and is due to alterations in systemic and renal hemodynamics. Serum creatinine-based estimation of kidney function is a key component of the Model for End-stage Liver Disease score in liver transplant candidates. Continuous renal replacement therapy is used in critically ill patients with liver failure and AKI. Simultaneous liver-kidney transplantation (SLK) may be required in patients with liver failure and prolonged AKI. Identification of appropriate candidates for SLK remains controversial.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 343-355 |
| Number of pages | 13 |
| Journal | Critical Care Clinics |
| Volume | 32 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jul 1 2016 |
All Science Journal Classification (ASJC) codes
- Critical Care and Intensive Care Medicine
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