Lactulose-induced pneumatosis intestinalis and pneumoperitoneum

Robert A. Goodman; Thomas Riley III

doi:10.1023/A:1012308911096

Lactulose-induced pneumatosis intestinalis and pneumoperitoneum

Robert A. Goodman, Thomas Riley III

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

A case of PI in a 57-year-old patient with colonic inertia treated with lactulose for PSE secondary to cirrhosis is described. The colonic inertia led to longer transit time. Retained lactulose and a build-up of carbon dioxide and hydrogen gas occurred in the setting of altered bacterial flora deficient in hydrogen metabolism. The increased gas pressure caused extravasation of air into the intestine, causing PI with pneumoperitoneum. They both resolved with discontinuation of lactulose.

Original language	English (US)
Pages (from-to)	2549-2553
Number of pages	5
Journal	Digestive Diseases and Sciences
Volume	46
Issue number	11
DOIs	https://doi.org/10.1023/A:1012308911096
State	Published - 2001

All Science Journal Classification (ASJC) codes

Physiology
Gastroenterology

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10.1023/A:1012308911096

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title = "Lactulose-induced pneumatosis intestinalis and pneumoperitoneum",

abstract = "A case of PI in a 57-year-old patient with colonic inertia treated with lactulose for PSE secondary to cirrhosis is described. The colonic inertia led to longer transit time. Retained lactulose and a build-up of carbon dioxide and hydrogen gas occurred in the setting of altered bacterial flora deficient in hydrogen metabolism. The increased gas pressure caused extravasation of air into the intestine, causing PI with pneumoperitoneum. They both resolved with discontinuation of lactulose.",

author = "Goodman, {Robert A.} and {Riley III}, Thomas",

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AU - Riley III, Thomas

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AB - A case of PI in a 57-year-old patient with colonic inertia treated with lactulose for PSE secondary to cirrhosis is described. The colonic inertia led to longer transit time. Retained lactulose and a build-up of carbon dioxide and hydrogen gas occurred in the setting of altered bacterial flora deficient in hydrogen metabolism. The increased gas pressure caused extravasation of air into the intestine, causing PI with pneumoperitoneum. They both resolved with discontinuation of lactulose.

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JO - Digestive Diseases and Sciences

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ER -

Lactulose-induced pneumatosis intestinalis and pneumoperitoneum

Abstract

All Science Journal Classification (ASJC) codes

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