Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury

Kit Neikirk; Adaku C. Ume; Praveena Prasad; Andrea G. Marshall; Jananie Rockwood; Tara Yesomi Wenegieme; Kelia E. McMichael; Melanie R. McReynolds; Clintoria R. Williams; Antentor Hinton

doi:10.1111/acel.14019

Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury

Kit Neikirk, Adaku C. Ume, Praveena Prasad, Andrea G. Marshall, Jananie Rockwood, Tara Yesomi Wenegieme, Kelia E. McMichael, Melanie R. McReynolds, Clintoria R. Williams, Antentor Hinton

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

Recently, latent transforming growth factor beta binding protein 4 (LTBP4) was implicated in the pathogenesis of renal damage through its modulation of mitochondrial dynamics. The seminal article written by Su et al. entitled “LTBP4 (Latent Transforming Growth Factor Beta Binding Protein 4) Protects Against Renal Fibrosis via Mitochondrial and Vascular Impacts” uncovers LTBP4's renoprotective role against acute kidney injury via modulating mitochondrial dynamics. Recently, LTBP4 has emerged as a driver in the mitochondrial-dependent modulation of age-related organ pathologies. This article aims to expand our understanding of LTBP4's diverse roles in these diseases in the context of these recent findings.

Original language	English (US)
Article number	e14019
Journal	Aging cell
Volume	22
Issue number	12
DOIs	https://doi.org/10.1111/acel.14019
State	Published - Dec 2023

All Science Journal Classification (ASJC) codes

Aging
Cell Biology

Access to Document

10.1111/acel.14019

Cite this

@article{b7d277f0a5284a578a863f229611c450,

title = "Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury",

abstract = "Recently, latent transforming growth factor beta binding protein 4 (LTBP4) was implicated in the pathogenesis of renal damage through its modulation of mitochondrial dynamics. The seminal article written by Su et al. entitled “LTBP4 (Latent Transforming Growth Factor Beta Binding Protein 4) Protects Against Renal Fibrosis via Mitochondrial and Vascular Impacts” uncovers LTBP4's renoprotective role against acute kidney injury via modulating mitochondrial dynamics. Recently, LTBP4 has emerged as a driver in the mitochondrial-dependent modulation of age-related organ pathologies. This article aims to expand our understanding of LTBP4's diverse roles in these diseases in the context of these recent findings.",

author = "Kit Neikirk and Ume, {Adaku C.} and Praveena Prasad and Marshall, {Andrea G.} and Jananie Rockwood and Wenegieme, {Tara Yesomi} and McMichael, {Kelia E.} and McReynolds, {Melanie R.} and Williams, {Clintoria R.} and Antentor Hinton",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.",

year = "2023",

month = dec,

doi = "10.1111/acel.14019",

language = "English (US)",

volume = "22",

journal = "Aging cell",

issn = "1474-9718",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "12",

}

TY - JOUR

T1 - Latent transforming growth factor beta binding protein 4

T2 - A regulator of mitochondrial function in acute kidney injury

AU - Neikirk, Kit

AU - Ume, Adaku C.

AU - Prasad, Praveena

AU - Marshall, Andrea G.

AU - Rockwood, Jananie

AU - Wenegieme, Tara Yesomi

AU - McMichael, Kelia E.

AU - McReynolds, Melanie R.

AU - Williams, Clintoria R.

AU - Hinton, Antentor

PY - 2023/12

Y1 - 2023/12

N2 - Recently, latent transforming growth factor beta binding protein 4 (LTBP4) was implicated in the pathogenesis of renal damage through its modulation of mitochondrial dynamics. The seminal article written by Su et al. entitled “LTBP4 (Latent Transforming Growth Factor Beta Binding Protein 4) Protects Against Renal Fibrosis via Mitochondrial and Vascular Impacts” uncovers LTBP4's renoprotective role against acute kidney injury via modulating mitochondrial dynamics. Recently, LTBP4 has emerged as a driver in the mitochondrial-dependent modulation of age-related organ pathologies. This article aims to expand our understanding of LTBP4's diverse roles in these diseases in the context of these recent findings.

AB - Recently, latent transforming growth factor beta binding protein 4 (LTBP4) was implicated in the pathogenesis of renal damage through its modulation of mitochondrial dynamics. The seminal article written by Su et al. entitled “LTBP4 (Latent Transforming Growth Factor Beta Binding Protein 4) Protects Against Renal Fibrosis via Mitochondrial and Vascular Impacts” uncovers LTBP4's renoprotective role against acute kidney injury via modulating mitochondrial dynamics. Recently, LTBP4 has emerged as a driver in the mitochondrial-dependent modulation of age-related organ pathologies. This article aims to expand our understanding of LTBP4's diverse roles in these diseases in the context of these recent findings.

UR - http://www.scopus.com/inward/record.url?scp=85176928505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85176928505&partnerID=8YFLogxK

U2 - 10.1111/acel.14019

DO - 10.1111/acel.14019

M3 - Short survey

C2 - 37960979

AN - SCOPUS:85176928505

SN - 1474-9718

VL - 22

JO - Aging cell

JF - Aging cell

IS - 12

M1 - e14019

ER -

Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this