Left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation

Rizma Jalees Bajwa, Lara Kovell, Jon R. Resar, Armin Arbab-Zadeh, Kaushik Mandal, Hugh Calkins, Ronald D. Berger

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


Atrial fibrillation (AF) is a commonly sustained atrial arrhythmia with associated morbidity and mortality. AF is associated with increased risk of thromboembolism and stroke, requiring use of anticoagulation. Anticoagulation decreases the risk of stroke but is associated with a higher risk of bleeding, necessitating discontinuation in some patients. The left atrial appendage is the likely source of thrombus in the majority of patients with AF. This has led to the development of left atrial appendage occlusion as a means to reduce stroke risk in patients who have a contraindication to long-term anticoagulation. Multiple implantable devices have surfaced in the last few years, with some promising prospects. The main purpose of this review is to highlight the indications and use of these devices for left atrial appendage occlusion.

Original languageEnglish (US)
Pages (from-to)825-831
Number of pages7
JournalClinical Cardiology
Issue number10
StatePublished - Oct 2017

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine


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