TY - JOUR
T1 - Leptin, hunger, and body weight
T2 - Influence of gender, tobacco smoking, and smoking abstinence
AU - Klein, Laura Cousino
AU - Corwin, Elizabeth J.
AU - Ceballos, Rachel M.
N1 - Funding Information:
This research was conducted at The Pennsylvania State University and was supported by a Penn State interdisciplinary seed grant awarded to LCK and EJC (#223-15 3605). The Penn State General Clinical Research Center Cytokine Core Laboratory at the Noll Physiological Research Laboratory (NIH Grant M01-RR-10732) provided support for the leptin assays. Manuscript preparation by LCK was supported by the National Institute on Drug Abuse #DA15114-0. We thank K. Rickelman for assistance with data collection, Dr. Elizabeth J. Susman for providing comments on an earlier version of this manuscript, the Biobehavioral Health Studies Laboratory for assistance with data management, and Richard Ball for conducting the leptin assays.
PY - 2004/7
Y1 - 2004/7
N2 - Leptin is a hormone involved in body weight and hunger regulation, and may contribute to the inverse relationship between cigarette smoking and body weight. Leptin levels, body mass indices (BMIs), and hunger ratings were determined in 22 nonsmokers (12 male, 10 female) and 19 cigarette smokers (11 male, 8 female). Smokers were tested after ad lib smoking and following a 24-h smoking abstinence period; nonsmokers came to the laboratory once. Leptin levels were not different among the groups. Hunger ratings, however, were higher after smoking abstinence compared to after ad lib smoking and nonsmokers (Ps<.05); levels of hunger did not differ between ad lib smokers and nonsmokers. Men reported higher hunger levels than did women, but women had higher serum leptin levels than did men, regardless of smoking condition (P<.05). Leptin levels were correlated with BMI (P<.05) among smokers only. This first study on leptin responses in female smokers suggests that leptin levels do not change following a 24-h smoking abstinence period and that leptin may not contribute to increased hunger following smoking abstinence.
AB - Leptin is a hormone involved in body weight and hunger regulation, and may contribute to the inverse relationship between cigarette smoking and body weight. Leptin levels, body mass indices (BMIs), and hunger ratings were determined in 22 nonsmokers (12 male, 10 female) and 19 cigarette smokers (11 male, 8 female). Smokers were tested after ad lib smoking and following a 24-h smoking abstinence period; nonsmokers came to the laboratory once. Leptin levels were not different among the groups. Hunger ratings, however, were higher after smoking abstinence compared to after ad lib smoking and nonsmokers (Ps<.05); levels of hunger did not differ between ad lib smokers and nonsmokers. Men reported higher hunger levels than did women, but women had higher serum leptin levels than did men, regardless of smoking condition (P<.05). Leptin levels were correlated with BMI (P<.05) among smokers only. This first study on leptin responses in female smokers suggests that leptin levels do not change following a 24-h smoking abstinence period and that leptin may not contribute to increased hunger following smoking abstinence.
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U2 - 10.1016/j.addbeh.2004.02.023
DO - 10.1016/j.addbeh.2004.02.023
M3 - Article
C2 - 15219336
AN - SCOPUS:3042695547
SN - 0306-4603
VL - 29
SP - 921
EP - 927
JO - Addictive Behaviors
JF - Addictive Behaviors
IS - 5
ER -
