Lesions of the pontine parabrachial nuclei eliminate successive negative contrast effects in rats

P. S. Grigson, A. C. Spector, R. Norgren

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Rats shifted from a high to a low concentration of sucrose make fewer licks for the low concentration than rats that experience only the low concentration of sucrose. This phenomenon, referred to as successive negative contrast, is eliminated after bilateral electrolytic lesions of the amygdala. Because the amygdala receives direct projections from the gustatory zone of the parabrachial nuclei of the pons (PBN), this experiment was designed to examine this phenomenon in rats with electrophysiologically guided bilateral electrolytic lesions of the PBN. The results of this experiment showed that lesions of the PBN fully prevent contrast in rats shifted from the high to the low concentration of sucrose. Thus, an intact PBN is essential for the occurrence of successive negative contrast effects in rats.

Original languageEnglish (US)
Pages (from-to)714-723
Number of pages10
JournalBehavioral Neuroscience
Volume108
Issue number4
DOIs
StatePublished - 1994

All Science Journal Classification (ASJC) codes

  • Behavioral Neuroscience

Fingerprint

Dive into the research topics of 'Lesions of the pontine parabrachial nuclei eliminate successive negative contrast effects in rats'. Together they form a unique fingerprint.

Cite this