TY - JOUR
T1 - Less Common Colorectal Cancer Predisposition Syndromes
AU - McGarrity, Thomas J.
AU - Amos, Christopher
PY - 2009/10
Y1 - 2009/10
N2 - A variety of syndromes confer increased risk for intestinal polyp development, outside the more commonly occurring syndromes. Each of these uncommon syndromes predispose to pathognomonic histologies that are uncommonly observed. Accurate diagnosis of these syndromes is contingent on higher-level pathology review, evaluation of signs and symptoms beyond sole consideration of the polyps, and collection of a detailed family history. When a genetic mutation can be identified in the proband, the management of intestinal and extra-intestinal cancer screening can be more appropriately tailored.
AB - A variety of syndromes confer increased risk for intestinal polyp development, outside the more commonly occurring syndromes. Each of these uncommon syndromes predispose to pathognomonic histologies that are uncommonly observed. Accurate diagnosis of these syndromes is contingent on higher-level pathology review, evaluation of signs and symptoms beyond sole consideration of the polyps, and collection of a detailed family history. When a genetic mutation can be identified in the proband, the management of intestinal and extra-intestinal cancer screening can be more appropriately tailored.
UR - http://www.scopus.com/inward/record.url?scp=70349330757&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349330757&partnerID=8YFLogxK
U2 - 10.1016/j.soc.2009.07.005
DO - 10.1016/j.soc.2009.07.005
M3 - Review article
C2 - 19793572
AN - SCOPUS:70349330757
SN - 1055-3207
VL - 18
SP - 647
EP - 661
JO - Surgical Oncology Clinics of North America
JF - Surgical Oncology Clinics of North America
IS - 4
ER -
