TY - JOUR
T1 - Levodopa therapy improves motor function in HIV-infected children with extrapyramidal syndromes
AU - Mintz, M.
AU - Tardieu, M.
AU - Hoyt, L.
AU - McSherry, G.
AU - Mendelson, J.
AU - Oleske, J.
PY - 1996/12
Y1 - 1996/12
N2 - Five children with human immunodeficiency virus type-1 (HIV-1) infection, aged 4 to 13 years, manifested extrapyramidal dysfunction characterized by rigidity/stiffness, ambulation difficulties/shuffling gait, dysarthria/drooling/swallowing dysfunction, hypomimetic/inexpressive facies, and bradykinesia. Levodopa therapy caused an initial improvement in all symptoms, and the effect was sustained in most patients. Levodopa is a useful adjunctive therapy in HIV-1 infected children with extrapyramidal syndromes, by enhancing motor function and improving their quality of life.
AB - Five children with human immunodeficiency virus type-1 (HIV-1) infection, aged 4 to 13 years, manifested extrapyramidal dysfunction characterized by rigidity/stiffness, ambulation difficulties/shuffling gait, dysarthria/drooling/swallowing dysfunction, hypomimetic/inexpressive facies, and bradykinesia. Levodopa therapy caused an initial improvement in all symptoms, and the effect was sustained in most patients. Levodopa is a useful adjunctive therapy in HIV-1 infected children with extrapyramidal syndromes, by enhancing motor function and improving their quality of life.
UR - http://www.scopus.com/inward/record.url?scp=0029730804&partnerID=8YFLogxK
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U2 - 10.1212/WNL.47.6.1583
DO - 10.1212/WNL.47.6.1583
M3 - Article
C2 - 8960752
AN - SCOPUS:0029730804
SN - 0028-3878
VL - 47
SP - 1583
EP - 1585
JO - Neurology
JF - Neurology
IS - 6
ER -