Lichen planus associated with neoplasia: A cell-mediated immune response to tumor antigens?

Thomas N. Helm; Charles Camisa; Aries Y. Liu; Rafael Valenzuela; Wilma F. Bergfeld

doi:10.1016/S0190-9622(94)70020-6

Lichen planus associated with neoplasia: A cell-mediated immune response to tumor antigens?

Thomas N. Helm, Charles Camisa, Aries Y. Liu, Rafael Valenzuela, Wilma F. Bergfeld

Department of Dermatology

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Background: Individual case reports have suggested an occasional association of lichen planus with internal malignancy. Objective: Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed. Methods: Serologic and immunopathologic studies were conducted. Results: No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected. Conclusion:Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.

Original language	English (US)
Pages (from-to)	219-224
Number of pages	6
Journal	Journal of the American Academy of Dermatology
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/S0190-9622(94)70020-6
State	Published - 1994

All Science Journal Classification (ASJC) codes

Dermatology

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10.1016/S0190-9622(94)70020-6

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title = "Lichen planus associated with neoplasia: A cell-mediated immune response to tumor antigens?",

abstract = "Background: Individual case reports have suggested an occasional association of lichen planus with internal malignancy. Objective: Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed. Methods: Serologic and immunopathologic studies were conducted. Results: No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected. Conclusion:Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.",

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T2 - A cell-mediated immune response to tumor antigens?

AU - Helm, Thomas N.

AU - Camisa, Charles

AU - Liu, Aries Y.

AU - Valenzuela, Rafael

AU - Bergfeld, Wilma F.

PY - 1994

Y1 - 1994

N2 - Background: Individual case reports have suggested an occasional association of lichen planus with internal malignancy. Objective: Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed. Methods: Serologic and immunopathologic studies were conducted. Results: No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected. Conclusion:Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.

AB - Background: Individual case reports have suggested an occasional association of lichen planus with internal malignancy. Objective: Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed. Methods: Serologic and immunopathologic studies were conducted. Results: No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected. Conclusion:Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.

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Lichen planus associated with neoplasia: A cell-mediated immune response to tumor antigens?

Abstract

All Science Journal Classification (ASJC) codes

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