Lichen planus associated with neoplasia: A cell-mediated immune response to tumor antigens?

Thomas N. Helm; Charles Camisa; Aries Y. Liu; Rafael Valenzuela; Wilma F. Bergfeld

doi:10.1016/S0190-9622(94)70020-6

Lichen planus associated with neoplasia: A cell-mediated immune response to tumor antigens?

Thomas N. Helm, Charles Camisa, Aries Y. Liu, Rafael Valenzuela, Wilma F. Bergfeld

Department of Dermatology

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Background: Individual case reports have suggested an occasional association of lichen planus with internal malignancy. Objective: Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed. Methods: Serologic and immunopathologic studies were conducted. Results: No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected. Conclusion:Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.

Original language	English (US)
Pages (from-to)	219-224
Number of pages	6
Journal	Journal of the American Academy of Dermatology
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/S0190-9622(94)70020-6
State	Published - 1994

All Science Journal Classification (ASJC) codes

Dermatology

Access to Document

10.1016/S0190-9622(94)70020-6

Cite this

@article{ad4296cde5844bbbaacc8e9bfa7191f1,

title = "Lichen planus associated with neoplasia: A cell-mediated immune response to tumor antigens?",

abstract = "Background: Individual case reports have suggested an occasional association of lichen planus with internal malignancy. Objective: Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed. Methods: Serologic and immunopathologic studies were conducted. Results: No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected. Conclusion:Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.",

author = "Helm, \{Thomas N.\} and Charles Camisa and Liu, \{Aries Y.\} and Rafael Valenzuela and Bergfeld, \{Wilma F.\}",

year = "1994",

doi = "10.1016/S0190-9622(94)70020-6",

language = "English (US)",

volume = "30",

pages = "219--224",

journal = "Journal of the American Academy of Dermatology",

issn = "0190-9622",

publisher = "Elsevier Inc.",

number = "2",

}

TY - JOUR

T1 - Lichen planus associated with neoplasia

T2 - A cell-mediated immune response to tumor antigens?

AU - Helm, Thomas N.

AU - Camisa, Charles

AU - Liu, Aries Y.

AU - Valenzuela, Rafael

AU - Bergfeld, Wilma F.

PY - 1994

Y1 - 1994

N2 - Background: Individual case reports have suggested an occasional association of lichen planus with internal malignancy. Objective: Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed. Methods: Serologic and immunopathologic studies were conducted. Results: No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected. Conclusion:Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.

AB - Background: Individual case reports have suggested an occasional association of lichen planus with internal malignancy. Objective: Our purpose was to describe five patients with a neoplastic disease in whom lichen planus developed. Methods: Serologic and immunopathologic studies were conducted. Results: No evidence of autoantibody production characteristic of paraneoplastic pemphigus was found, and antibodies reactive with basal cell keratinocytes were not detected. Conclusion:Lichen planus may be rarely induced by neoplasia. A cell-mediated immune reaction possibly causes this phenomenon.

UR - https://www.scopus.com/pages/publications/0028006189

UR - https://www.scopus.com/inward/citedby.url?scp=0028006189&partnerID=8YFLogxK

U2 - 10.1016/S0190-9622(94)70020-6

DO - 10.1016/S0190-9622(94)70020-6

M3 - Article

C2 - 8288781

AN - SCOPUS:0028006189

SN - 0190-9622

VL - 30

SP - 219

EP - 224

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

IS - 2

ER -

Lichen planus associated with neoplasia: A cell-mediated immune response to tumor antigens?

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this