Light activated patterning of dye-labeled molecules on surfaces

Matthew A. Holden, Paul S. Cremer

Research output: Contribution to journalArticlepeer-review

93 Scopus citations


This Communication describes a novel method for patterning proteins, ligands, or other organic/inorganic species onto solid substrates. The process works by linking the moiety of interest to a fluorophore that can be subsequently photobleached and bound to the interface. The technique can be performed in aqueous solution and allows several species to be addressed onto the surface simultaneously by using different frequencies of light. Because the method can be used with fluorophores excited by visible light, shorter and more damaging wavelengths can be avoided.

Original languageEnglish (US)
Pages (from-to)8074-8075
Number of pages2
JournalJournal of the American Chemical Society
Issue number27
StatePublished - Jul 9 2003

All Science Journal Classification (ASJC) codes

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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