Abstract
Screening for medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency by urinary 3-phenylproplonylglycine may not be reliable in early infancy because young infants are not colonized with adult-type colonic flora. In this study we delineated the microbes that produce 3-phenylpropionic acid, the precursor of 3-phenylpropionylglycine. We found that the use of some antibiotics may alter gut flora, thereby confounding this method of screening for MCAD deficiency.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 100-103 |
| Number of pages | 4 |
| Journal | The Journal of Pediatrics |
| Volume | 122 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1993 |
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
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