TY - GEN
T1 - Live capture of circulating tumor cells from human blood by a splitable 3D parylene membrane filtration device
AU - Lu, Bo
AU - Zheng, Siyang
AU - Xie, Shuang
AU - Tai, Yu Chong
PY - 2009
Y1 - 2009
N2 - In this work, a novel splitable 3D parylene membrane filter was designed, fabricated and tested. Viable tumor cells can be captured and kept alive for at least 20 days. Due to the "gap trapping mechanism" and splitable feature, we can release and collect trapped tumor cells from device after filtration. Combination of high capture efficiency, high throughput, low cost and viable capture makes it a promising candidate for detection and further study of circulating tumor cells.
AB - In this work, a novel splitable 3D parylene membrane filter was designed, fabricated and tested. Viable tumor cells can be captured and kept alive for at least 20 days. Due to the "gap trapping mechanism" and splitable feature, we can release and collect trapped tumor cells from device after filtration. Combination of high capture efficiency, high throughput, low cost and viable capture makes it a promising candidate for detection and further study of circulating tumor cells.
UR - http://www.scopus.com/inward/record.url?scp=84901756389&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901756389&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84901756389
SN - 9780979806421
T3 - Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 588
EP - 590
BT - Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
Y2 - 1 November 2009 through 5 November 2009
ER -