Local anesthesia with intravenous sedation for surgical repair of selected open globe injuries

Ingrid U. Scott, Cathleen M. Mccabe, Harry W. Flynn, Dagmar R. Lemus, Joyce C. Schiffman, Dale S. Reynolds, Mauricio B. Pereira, Armando Belfort, Steven Gayer

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


PURPOSE: To report factors associated with the use of local anesthesia with intravenous sedation (local anesthesia/sedation) rather than general anesthesia for surgery for open globe injuries in adult reparable eyes. DESIGN: Retrospective, nonrandomized, comparative case series. METHODS: Medical records were reviewed of all patients with open globe injuries repaired at Bascom Palmer Eye Institute between 1995 and 1999. "Adult reparable eyes" (eyes in patients ≥18 years of age, not treated with primary enucleation or evisceration, followed up ≥2 months) were included. RESULTS: In all, 220 eyes of 218 patients met inclusion criteria. General anesthesia was employed in 80 of 200 (36%) and local anesthesia/sedation in 140 of 220 (64%). Patients who had local anesthesia/sedation were significantly more likely to have an intraocular foreign body (31% vs 14%; P = .010, chi-square test), better presenting visual acuity (1.8 logMAR [logarithm of the minimum angle of resolution] units vs 2.5 logMAR units; P < .001, t test), more anterior wound location (75% corneal/limbal vs 65%; P = .003, chi-square), shorter wound length (6.3mm vs 10.8mm; P < .001, t test), and dehiscence of previous surgical wound (26% vs 12%; P = .021, chi-square) and were significantly less likely to have an afferent pupillary defect (22% vs 51%; P < .001, chi-square). There was no anesthesia-related complication in either group. The local anesthesia/sedation group had a shorter mean operating time than did the general anesthesia group (78 minutes vs 117 minutes; P < .001, t test). The general anesthesia group had a longer mean follow-up than the local anesthesia/sedation group (20.2 months vs 13.9 months, respectively; P = .002, t test). Change in visual acuity between the presenting and final examinations was similar for open globe injuries repaired with general anesthesia compared with local anesthesia/sedation (0.94 vs 0.72 logMAR units of visual acuity, respectively; P = .16, t test). CONCLUSIONS: Local anesthesia/sedation is a reasonable alternative to general anesthesia for selected patients with open globe injuries.

Original languageEnglish (US)
Pages (from-to)707-711
Number of pages5
JournalAmerican Journal of Ophthalmology
Issue number5
StatePublished - Nov 1 2002

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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