Long Objective Sleep Duration is a Marker of Cognitive Impairment in Older Adults: Findings from the Cretan Aging Cohort

Maria Basta, Izolde Bouloukaki, Eleni Skourti, Alexandros Zampetakis, Christina Alexopoulou, Andronikos Ganiaris, Marina Aligizaki, Ioannis Zaganas, Panagiotis Simos, Alexandros Vgontzas

Research output: Contribution to journalArticlepeer-review

Abstract

We examined associations between objective sleep duration and cognitive status in older adults initially categorized as cognitively non-impaired (CNI, n = 57) or diagnosed with mild cognitive impairment (MCI, n = 53). On follow-up, 8 years later, all participants underwent neuropsychiatric/neuropsychological evaluation and 7-day 24-h actigraphy. On re-assessment 62.7% of participants were cognitively declined. Patients who developed dementia had significantly longer night total sleep time (TST) than persons with MCI who, in turn, had longer night TST than CNI participants. Objective long sleep duration is a marker of worse cognitive status in elderly with MCI/dementia and this association is very strong in older adults.

Original languageEnglish (US)
Pages (from-to)927-934
Number of pages8
JournalJournal of Alzheimer's Disease Reports
Volume8
Issue number1
DOIs
StatePublished - May 27 2024

All Science Journal Classification (ASJC) codes

  • General Neuroscience
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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