The authors contrast variables that affect employee responses to a medical information system (MIS) six months vs. one year postimplementation. Data were collected from 45 employees who remained in the panel for 15 months. Multiple regression techniques were used to model factors that significantly influence variability in adaptation. Most of the independent variables that were previously demonstrated to influence short-term reactions were also important when examined six months later. In particular, personality traits, educational level, job mobility, age, and work shift appear to be key explanatory variables.