TY - JOUR
T1 - Longitudinal study of energy, neurosensory and eating responses durinG pregnancY (ENERGY cohort)
T2 - A study protocol
AU - McCormack, Jessica C.
AU - Roberts, Reece
AU - Garratt, Mike
AU - Wang, Ting
AU - Hayes, John
AU - Peng, Mei
N1 - Funding Information:
The study is supported by the New Zealand Royal Society Te Apārangi via Marsden Fund (MFP_UOO2119).
Funding Information:
Participants will be recruited through snowballing approaches. These include collaborations with local medical centres and maternity support organisations, traditional media (i.e., newspapers such as Otago Daily Times, Stuff. co.nz, and local radio stations), social media (i.e., Facebook, GoogleAds), flyers and posters in community spaces, participants from previous studies, and word of mouth.
Publisher Copyright:
© 2023 European Society for Clinical Nutrition and Metabolism
PY - 2023/4
Y1 - 2023/4
N2 - Background and aims: Physiological changes that occur during pregnancy can have long-term impacts on metabolism and neurosensory responses to food, which can impact nutrition and health outcomes. The ENERGY cohort is a longitudinal study that aims to capitalizes on pregnancy as a natural model of metabolic reprogramming in order to understand the neurosensory mechanisms underpinning links between metabolism and dietary behaviour. The study objectives are to test for multi-sensory shifts during pregnancy, and the effect of sensory changes on dietary choices and bodyweights, and to identify neurosensory mechanisms that determine macronutrient selection before and after pregnancy. Methods: A longitudinal cohort study involving 130 pregravid women planning to conceive with the next 12-months and 65 pregravid women with no short-term plans to conceive. Participants will be recruited from Dunedin and Auckland, New Zealand. The study will test for changes in diet, neurosensory outcomes, and metabolism across the reproductive cycle, from pre-pregnancy to 1-year post-pregnancy. Data will be collected at six timepoint throughout the pregnancy which will occur approximately every 3 months. The primary response variables will be changes in supra-threshold sensitivity across modalities, dietary intake, and metabolism between pre-pregnancy and post-pregnancy. Longitudinal data analysis will use linear mixed models to assess changes in the response outcomes over time adjusted for age, ethnicity, and socioeconomic status. Discussion: Understanding the relationship between metabolism, sensory processing, and macronutrient preferences will provide crucial insights into diet-related health issues, including obesity. This study will lead to the formation of a prospective research cohort that is unique to Aotearoa New Zealand, and will develop multidisciplinary skills that are increasingly necessary to addressing the obesity epidemic.
AB - Background and aims: Physiological changes that occur during pregnancy can have long-term impacts on metabolism and neurosensory responses to food, which can impact nutrition and health outcomes. The ENERGY cohort is a longitudinal study that aims to capitalizes on pregnancy as a natural model of metabolic reprogramming in order to understand the neurosensory mechanisms underpinning links between metabolism and dietary behaviour. The study objectives are to test for multi-sensory shifts during pregnancy, and the effect of sensory changes on dietary choices and bodyweights, and to identify neurosensory mechanisms that determine macronutrient selection before and after pregnancy. Methods: A longitudinal cohort study involving 130 pregravid women planning to conceive with the next 12-months and 65 pregravid women with no short-term plans to conceive. Participants will be recruited from Dunedin and Auckland, New Zealand. The study will test for changes in diet, neurosensory outcomes, and metabolism across the reproductive cycle, from pre-pregnancy to 1-year post-pregnancy. Data will be collected at six timepoint throughout the pregnancy which will occur approximately every 3 months. The primary response variables will be changes in supra-threshold sensitivity across modalities, dietary intake, and metabolism between pre-pregnancy and post-pregnancy. Longitudinal data analysis will use linear mixed models to assess changes in the response outcomes over time adjusted for age, ethnicity, and socioeconomic status. Discussion: Understanding the relationship between metabolism, sensory processing, and macronutrient preferences will provide crucial insights into diet-related health issues, including obesity. This study will lead to the formation of a prospective research cohort that is unique to Aotearoa New Zealand, and will develop multidisciplinary skills that are increasingly necessary to addressing the obesity epidemic.
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U2 - 10.1016/j.clnesp.2023.01.033
DO - 10.1016/j.clnesp.2023.01.033
M3 - Article
C2 - 36963873
AN - SCOPUS:85147972420
SN - 2405-4577
VL - 54
SP - 271
EP - 276
JO - Clinical Nutrition ESPEN
JF - Clinical Nutrition ESPEN
ER -
