Low-temperature sol-gel-derived nanosilver-embedded silane coating as biofilm inhibitor

A. Babapour, B. Yang, S. Bahang, W. Cao

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Silver nanocomposite coatings are prepared by the sol-gel method for the prevention of biofilm formation on the surface of medical implanted devices. High-temperature processing of such coatings can lead to diffusion of nanosilver and reduce the amount of available silver particles for long-term effects. Using a low-temperature sol-gel method, we have successfully prepared silane-based matrices, phenyltriethoxysilane (PhTEOS), containing different amounts of Ag nanoparticles. The incorporation of a silver salt into the sol-gel matrix resulted in a desired silver release rate, i.e. high initial release rate followed by a lower sustained release for more than 15days, as determined by inductively coupled plasma mass spectrometry (ICP-MS). Scanning electron microscopy (SEM) has been employed to investigate the morphology of the film surfaces before and after immersion in a nutrient-rich bacterial suspension of approximately 108CFUml-1, which was incubated for up to 30days at 37 °C. It was found that thin films containing 35nm particles could prevent the formation of biofilm for over 30days. The presence of surface silver before and after 3, 9 and 15days immersion was confirmed by x-ray photoelectron spectroscopy (XPS).

Original languageEnglish (US)
Article number155602
Issue number15
StatePublished - Apr 15 2011

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • General Chemistry
  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering
  • Electrical and Electronic Engineering


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