Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration

Daniel H. Cortes; Jeremy F. Magland; Alexander C. Wright; Victor H. Barocas; Dawn M. Elliott

doi:10.1109/NEBC.2012.6206973

Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration

Daniel H. Cortes, Jeremy F. Magland, Alexander C. Wright, Victor H. Barocas, Dawn M. Elliott

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Intervertebral disc degeneration is a cell-mediated process that results in the disruption of its function. These changes are difficult to overturn; consequently, early diagnosis is key for the success of any treatment. Clinically, disc degeneration is diagnosed by analyzing morphological changes characteristic of moderate to advanced stages of degeneration. Therefore, there is a need of a reliable biomarker to characterize the compositional and structural integrity of the disc in early stages of degeneration. In this study, shear modulus is proposed as a new biomarker for disc degeneration and a non-invasive method to measure this mechanical property is presented.

Original language	English (US)
Title of host publication	2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012
Pages	83-84
Number of pages	2
DOIs	https://doi.org/10.1109/NEBC.2012.6206973
State	Published - 2012
Event	38th Annual Northeast Bioengineering Conference, NEBEC 2012 - Philadelphia, PA, United States Duration: Mar 16 2012 → Mar 18 2012

Publication series

Name	2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012

Other

Other	38th Annual Northeast Bioengineering Conference, NEBEC 2012
Country/Territory	United States
City	Philadelphia, PA
Period	3/16/12 → 3/18/12

All Science Journal Classification (ASJC) codes

Bioengineering

Access to Document

10.1109/NEBC.2012.6206973

Cite this

Cortes, D. H., Magland, J. F., Wright, A. C., Barocas, V. H., & Elliott, D. M. (2012). Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration. In 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012 (pp. 83-84). Article 6206973 (2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012). https://doi.org/10.1109/NEBC.2012.6206973

@inproceedings{4ab12fec69764a77be82cca305276600,

title = "Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration",

abstract = "Intervertebral disc degeneration is a cell-mediated process that results in the disruption of its function. These changes are difficult to overturn; consequently, early diagnosis is key for the success of any treatment. Clinically, disc degeneration is diagnosed by analyzing morphological changes characteristic of moderate to advanced stages of degeneration. Therefore, there is a need of a reliable biomarker to characterize the compositional and structural integrity of the disc in early stages of degeneration. In this study, shear modulus is proposed as a new biomarker for disc degeneration and a non-invasive method to measure this mechanical property is presented.",

author = "Cortes, {Daniel H.} and Magland, {Jeremy F.} and Wright, {Alexander C.} and Barocas, {Victor H.} and Elliott, {Dawn M.}",

year = "2012",

doi = "10.1109/NEBC.2012.6206973",

language = "English (US)",

isbn = "9781467311410",

series = "2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012",

pages = "83--84",

booktitle = "2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012",

note = "38th Annual Northeast Bioengineering Conference, NEBEC 2012 ; Conference date: 16-03-2012 Through 18-03-2012",

}

Cortes, DH, Magland, JF, Wright, AC, Barocas, VH & Elliott, DM 2012, Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration. in 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012., 6206973, 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012, pp. 83-84, 38th Annual Northeast Bioengineering Conference, NEBEC 2012, Philadelphia, PA, United States, 3/16/12. https://doi.org/10.1109/NEBC.2012.6206973

Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration. / Cortes, Daniel H.; Magland, Jeremy F.; Wright, Alexander C. et al.
2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012. 2012. p. 83-84 6206973 (2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration

AU - Cortes, Daniel H.

AU - Magland, Jeremy F.

AU - Wright, Alexander C.

AU - Barocas, Victor H.

AU - Elliott, Dawn M.

PY - 2012

Y1 - 2012

N2 - Intervertebral disc degeneration is a cell-mediated process that results in the disruption of its function. These changes are difficult to overturn; consequently, early diagnosis is key for the success of any treatment. Clinically, disc degeneration is diagnosed by analyzing morphological changes characteristic of moderate to advanced stages of degeneration. Therefore, there is a need of a reliable biomarker to characterize the compositional and structural integrity of the disc in early stages of degeneration. In this study, shear modulus is proposed as a new biomarker for disc degeneration and a non-invasive method to measure this mechanical property is presented.

AB - Intervertebral disc degeneration is a cell-mediated process that results in the disruption of its function. These changes are difficult to overturn; consequently, early diagnosis is key for the success of any treatment. Clinically, disc degeneration is diagnosed by analyzing morphological changes characteristic of moderate to advanced stages of degeneration. Therefore, there is a need of a reliable biomarker to characterize the compositional and structural integrity of the disc in early stages of degeneration. In this study, shear modulus is proposed as a new biomarker for disc degeneration and a non-invasive method to measure this mechanical property is presented.

UR - http://www.scopus.com/inward/record.url?scp=84862748423&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84862748423&partnerID=8YFLogxK

U2 - 10.1109/NEBC.2012.6206973

DO - 10.1109/NEBC.2012.6206973

M3 - Conference contribution

AN - SCOPUS:84862748423

SN - 9781467311410

T3 - 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012

SP - 83

EP - 84

BT - 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012

T2 - 38th Annual Northeast Bioengineering Conference, NEBEC 2012

Y2 - 16 March 2012 through 18 March 2012

ER -

Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration

Abstract

Publication series

Other

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this