TY - JOUR
T1 - Magnetic resonance imaging findings in Ménière's disease
AU - Patel, V. A.
AU - Oberman, B. S.
AU - Zacharia, T. T.
AU - Isildak, H.
N1 - Publisher Copyright:
© JLO (1984) Limited 2017.
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Objectives: To identify and evaluate cranial magnetic resonance imaging findings associated with Ménière's disease. Methods: Seventy-eight patients with a documented diagnosis of Ménière's disease and 35 controls underwent 1.5 T or 3 T magnetic resonance imaging of the brain. Patients also underwent otological, vestibular and audiometric examinations. Results: Lack of visualisation of the left and right vestibular aqueducts was identified as statistically significant amongst Ménière's disease patients (left, p = 0.0001, odds ratio = 0.02; right, p = 0.0004, odds ratio = 0.03). Both vestibular aqueducts were of abnormal size in the Ménière's disease group, albeit with left-sided significance (left, p = 0.008, odds ratio = 10.91; right, p = 0.49, odds ratio = 2.47). Conclusion: Lack of vestibular aqueduct visualisation on magnetic resonance imaging was statistically significant in Ménière's disease patients compared to the general population. The study findings suggest that magnetic resonance imaging can be useful to rule out retrocochlear pathology and provide radiological data to support the clinical diagnosis of Ménière's disease.
AB - Objectives: To identify and evaluate cranial magnetic resonance imaging findings associated with Ménière's disease. Methods: Seventy-eight patients with a documented diagnosis of Ménière's disease and 35 controls underwent 1.5 T or 3 T magnetic resonance imaging of the brain. Patients also underwent otological, vestibular and audiometric examinations. Results: Lack of visualisation of the left and right vestibular aqueducts was identified as statistically significant amongst Ménière's disease patients (left, p = 0.0001, odds ratio = 0.02; right, p = 0.0004, odds ratio = 0.03). Both vestibular aqueducts were of abnormal size in the Ménière's disease group, albeit with left-sided significance (left, p = 0.008, odds ratio = 10.91; right, p = 0.49, odds ratio = 2.47). Conclusion: Lack of vestibular aqueduct visualisation on magnetic resonance imaging was statistically significant in Ménière's disease patients compared to the general population. The study findings suggest that magnetic resonance imaging can be useful to rule out retrocochlear pathology and provide radiological data to support the clinical diagnosis of Ménière's disease.
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U2 - 10.1017/S0022215117001086
DO - 10.1017/S0022215117001086
M3 - Article
C2 - 28583226
AN - SCOPUS:85020257794
SN - 0022-2151
VL - 131
SP - 602
EP - 607
JO - Journal of Laryngology and Otology
JF - Journal of Laryngology and Otology
IS - 7
ER -