TY - JOUR
T1 - Malaria Molecular Epidemiology
T2 - Lessons from the International Centers of Excellence for Malaria Research Network
AU - Escalante, Ananias A.
AU - Ferreira, Marcelo U.
AU - Vinetz, Joseph M.
AU - Volkman, Sarah K.
AU - Cui, Liwang
AU - Gamboa, Dionicia
AU - Krogstad, Donald J.
AU - Barry, Alyssa E.
AU - Carlton, Jane M.
AU - van Eijk, Anna Maria
AU - Pradhan, Khageswar
AU - Mueller, Ivo
AU - Greenhouse, Bryan
AU - Pacheco, M. Andreina
AU - Vallejo, Andres F.
AU - Herrera, Socrates
AU - Felger, Ingrid
N1 - Publisher Copyright:
Copyright © 2015 by The American Society of Tropical Medicine and Hygiene.
PY - 2015/9
Y1 - 2015/9
N2 - Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being carried out by the International Centers of Excellence for Malaria Research (ICEMR) network in a variety of malaria-endemic settings. First, we discuss various novel approaches to understand malaria incidence and gametocytemia, focusing on Plasmodium falciparum and Plasmodium vivax. Second, we describe and compare different parasite genotyping methods commonly used in malaria epidemiology and population genetics. Finally, we discuss potential applications of molecular epidemiological tools and methods toward malaria control and elimination efforts.
AB - Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being carried out by the International Centers of Excellence for Malaria Research (ICEMR) network in a variety of malaria-endemic settings. First, we discuss various novel approaches to understand malaria incidence and gametocytemia, focusing on Plasmodium falciparum and Plasmodium vivax. Second, we describe and compare different parasite genotyping methods commonly used in malaria epidemiology and population genetics. Finally, we discuss potential applications of molecular epidemiological tools and methods toward malaria control and elimination efforts.
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U2 - 10.4269/ajtmh.15-0005
DO - 10.4269/ajtmh.15-0005
M3 - Article
C2 - 26259945
AN - SCOPUS:84965084748
SN - 0002-9637
VL - 93
SP - 79
EP - 86
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 3
ER -