Malformations of cortical development

Sangam Kanekar, Michael Gent

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


The advent of high resolution MRI techniques has revolutionized the imaging of cortical malformations. Today, specific gene defects have been identified to be responsible for several of the developmental cortical malformations. In this article we have discussed the developmental cortical malformations under stages of proliferation, migration and organization. The relevant molecular genetics and its relationship to the cortical defects are also outlined. Neuroimaging features and relevant etio-pathogenesis of various cortical malformations are discussed in detail.

Original languageEnglish (US)
Pages (from-to)211-227
Number of pages17
JournalSeminars in Ultrasound, CT and MRI
Issue number3
StatePublished - Jun 2011

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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