Malignant hyperthermia due to anaesthesia

K. M. Lebedinskii, G. G. Prokopiev, S. M. Stepanenko, P. V. Dunts, I. V. Molchanov, A. M. Ovechkin, Yu S. Alexandrovich, V. V. Lomivorotov, N. P. Shen, A. V. Trembach, K. N. Zolotukhin, V. V. Pichugin, I. V. Boronina, A. V. Diordiev, S. I. Rostovtsev

Research output: Contribution to journalArticlepeer-review


Clinical guidelines address malignant hyperthermia, a rare pharmacogenetic syndrome triggered by volatile inhalational anesthetics and suxamethonium. Modern data concerning the mechanism of malignant hyperthermia development are presented, issues of syndrome clinical presentation and diagnosis are highlighted. Practical algorithm for anesthesiologist in case of malignant hyperthermia crisis is given, recommendations for identifying life-threatening syndromes and methods for their correction are presented. Prevention measures are also described. Medical care quality assessment criteria for the management of malignant hyperthermia patients are indicated.

Original languageEnglish (US)
Pages (from-to)6-18
Number of pages13
JournalRussian Journal of Anesthesiology and Reanimatology /Anesteziologiya i Reanimatologiya
Issue number6
StatePublished - 2023

All Science Journal Classification (ASJC) codes

  • Emergency Medicine
  • Anesthesiology and Pain Medicine

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