Malignant Tumors of the Skin and Subcutaneous Tissue in Children

Malignant tumors of the skin and subcutaneous tissue are rare in childhood. Prompt recognition can lead to improved cure rates. In the case of primary skin tumors, their presentation can signify a predisposing condition or syndrome. In the case of metastases, skin lesions can be the first sign of the underlying malignancy, providing an opportunity to diagnose and start treatment. Armed with knowledge of these varied skin manifestations, a clinician will have a heightened index of suspicion, which is essential. This chapter reviews malignant tumors of the skin in children, including primary skin malignancies, tumors that usually arise in other organs but that can present primarily in skin and subcutaneous tissues, and those that can metastasize to the skin. Predisposing factors and syndromes, important in this population, are discussed.