Malnutrition syndromes: A conundrum vs continuum

Gordon L. Jensen, Bruce Bistrian, Ronenn Roubenoff, Douglas C. Heimburger

Research output: Contribution to journalComment/debatepeer-review

147 Scopus citations


This provocative commentary critically examines historic definitions for adult malnutrition syndromes as they apply to developed countries with modern healthcare. To stimulate further discussion, the authors propose an updated approach that incorporates current understanding of the systemic inflammatory response to help guide assessment, diagnosis, and treatment. An appreciation of a continuum of inflammatory response in relation to malnutrition syndromes is described. This discussion serves to highlight a research agenda to address deficiencies in diagnostics, biomarkers, and therapeutics of inflammation in relation to malnutrition.

Original languageEnglish (US)
Pages (from-to)710-716
Number of pages7
JournalJournal of Parenteral and Enteral Nutrition
Issue number6
StatePublished - Nov 2009

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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