Mammary hibernoma: A rare entity

Meghan P. Riley, Dipti M. Karamchandani

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Hibernoma arising in the breast is rare and may present as an asymptomatic mass or may be detected by screening mammography. Four histologic types have been identified: typical, myxoid variant, spindle cell variant, and the lipoma-like variant. The most common "typical variant" is composed of pale to eosinophilic multivacuolated cells with interspersed univacuolar cells. Hibernomas are universally benign and are not known to recur or have an aggressive behavior, even in incompletely excised lesions. Hence, their clinical importance lies in distinguishing them from other benign and malignant breast neoplasms as well as inflammatory conditions that come into the histologic or radiologic differential. This review discusses the clinical features, radiologic and histopathologic characteristics, ancillary studies, suggested pathogenesis, differential diagnosis, and treatment of and prognosis for these uncommon lesions.

Original languageEnglish (US)
Pages (from-to)1565-1567
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Issue number12
StatePublished - Dec 2015

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


Dive into the research topics of 'Mammary hibernoma: A rare entity'. Together they form a unique fingerprint.

Cite this