TY - JOUR
T1 - Management of Non-tumoral Portal Vein Thrombosis in Patients with Cirrhosis
AU - Stine, Jonathan
AU - Northup, Patrick G.
PY - 2019/3/15
Y1 - 2019/3/15
N2 - Non-tumoral portal vein thrombosis (PVT) remains a highly relevant topic in the field of hepatology and liver transplantation with much surrounding controversy. Although multiple studies have shown that PVT is associated with adverse outcomes with increased morbidity and mortality rates, others have not reported the same clinical impact of PVT, arguing rather that incident PVT reflects worsening portal hypertension and the natural history of the disease. Despite this uncertainly, PVT is a dilemma facing the clinician on a daily basis often requiring a multidisciplinary team-based approach between hepatologists, transplant surgeons, interventional radiologists and hematologists. In this review, the authors provide a summary of the evidence supporting best clinical practices in the management of non-tumoral PVT in patients with cirrhosis.
AB - Non-tumoral portal vein thrombosis (PVT) remains a highly relevant topic in the field of hepatology and liver transplantation with much surrounding controversy. Although multiple studies have shown that PVT is associated with adverse outcomes with increased morbidity and mortality rates, others have not reported the same clinical impact of PVT, arguing rather that incident PVT reflects worsening portal hypertension and the natural history of the disease. Despite this uncertainly, PVT is a dilemma facing the clinician on a daily basis often requiring a multidisciplinary team-based approach between hepatologists, transplant surgeons, interventional radiologists and hematologists. In this review, the authors provide a summary of the evidence supporting best clinical practices in the management of non-tumoral PVT in patients with cirrhosis.
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U2 - 10.1007/s10620-018-5427-3
DO - 10.1007/s10620-018-5427-3
M3 - Review article
C2 - 30560339
AN - SCOPUS:85058845923
SN - 0163-2116
VL - 64
SP - 619
EP - 626
JO - Digestive Diseases and Sciences
JF - Digestive Diseases and Sciences
IS - 3
ER -