TY - JOUR
T1 - Mapping genes for plant structure, development and evolution
T2 - functional mapping meets ontology
AU - He, Qiuling
AU - Berg, Arthur
AU - Li, Yao
AU - Vallejos, C. Eduardo
AU - Wu, Rongling
N1 - Funding Information:
This work is partially supported by NSF/NIH Joint grant DMS/NIGMS-0540745, the Changjiang Scholarship Award at Beijing Forestry University, and the Innovation Fund of the Institutes of Food and Agricultural Sciences at the University of Florida.
PY - 2010/1
Y1 - 2010/1
N2 - One of the fundamental tasks in biology is the identification of genes that control the structure and developmental pattern of complex traits and their responses to the environment during trait development. Functional mapping provides a statistical means for detecting quantitative trait loci (QTLs) that underlie developmental traits, such as growth trajectories, and for testing the interplay between gene action and development. Here we describe how functional mapping and studies of plant ontology can be integrated so as to elucidate the expression mechanisms of QTLs that control plant growth, morphology, development, and adaptation to changing environments. This approach can also be used to construct an evo-devo framework for inferring the evolution of developmental traits.
AB - One of the fundamental tasks in biology is the identification of genes that control the structure and developmental pattern of complex traits and their responses to the environment during trait development. Functional mapping provides a statistical means for detecting quantitative trait loci (QTLs) that underlie developmental traits, such as growth trajectories, and for testing the interplay between gene action and development. Here we describe how functional mapping and studies of plant ontology can be integrated so as to elucidate the expression mechanisms of QTLs that control plant growth, morphology, development, and adaptation to changing environments. This approach can also be used to construct an evo-devo framework for inferring the evolution of developmental traits.
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U2 - 10.1016/j.tig.2009.11.004
DO - 10.1016/j.tig.2009.11.004
M3 - Review article
C2 - 19945189
AN - SCOPUS:72449170639
SN - 0168-9525
VL - 26
SP - 39
EP - 46
JO - Trends in Genetics
JF - Trends in Genetics
IS - 1
ER -