TY - JOUR
T1 - Mastocytosis
AU - Abid, Ayesha
AU - Malone, Michael A.
AU - Curci, Katherine
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Mastocytosis is a rare disease caused by excessive production of mast cells. Clinical presentation is variable, often based on the type of mastocytosis, but in all types of mastocytosis there seems to be an increase in the risk of anaphylaxis. Systemic mastocytosis is diagnosed based on bone marrow biopsy. Treatment is variable based on the type of mastocytosis, but trigger avoidance and anaphylaxis treatment are mainstays. There are no therapies that change the natural course of mastocytosis. For cutaneous mastocytosis, treatment is conservative and aimed at symptom relief.
AB - Mastocytosis is a rare disease caused by excessive production of mast cells. Clinical presentation is variable, often based on the type of mastocytosis, but in all types of mastocytosis there seems to be an increase in the risk of anaphylaxis. Systemic mastocytosis is diagnosed based on bone marrow biopsy. Treatment is variable based on the type of mastocytosis, but trigger avoidance and anaphylaxis treatment are mainstays. There are no therapies that change the natural course of mastocytosis. For cutaneous mastocytosis, treatment is conservative and aimed at symptom relief.
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U2 - 10.1016/j.pop.2016.04.007
DO - 10.1016/j.pop.2016.04.007
M3 - Review article
C2 - 27545739
AN - SCOPUS:84991069470
SN - 0095-4543
VL - 43
SP - 505
EP - 518
JO - Primary Care - Clinics in Office Practice
JF - Primary Care - Clinics in Office Practice
IS - 3
ER -