Mature homogeneous erythropoietin-level building blocks by chemical synthesis: the EPO 114-166 glycopeptide domain, presenting the O-linked glycophorin

Jiehao Chen; Gong Chen; Bin Wu; Qian Wan; Zhongping Tan; Zihao Hua; Samuel J. Danishefsky

doi:10.1016/j.tetlet.2006.09.045

Mature homogeneous erythropoietin-level building blocks by chemical synthesis: the EPO 114-166 glycopeptide domain, presenting the O-linked glycophorin

Jiehao Chen
, Gong Chen
, Bin Wu
, Qian Wan
, Zhongping Tan
, Zihao Hua
, Samuel J. Danishefsky

Chemistry

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

A synthesis of EPO 114-166 glycopeptide (1), presenting the O-linked glycophorin of erythropoietin, is described.

Original language	English (US)
Pages (from-to)	8013-8016
Number of pages	4
Journal	Tetrahedron Letters
Volume	47
Issue number	46
DOIs	https://doi.org/10.1016/j.tetlet.2006.09.045
State	Published - Nov 13 2006

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2006.09.045

Cite this

@article{65c8ea5e9f964e0fa84cc26d090741cc,

title = "Mature homogeneous erythropoietin-level building blocks by chemical synthesis: the EPO 114-166 glycopeptide domain, presenting the O-linked glycophorin",

abstract = "A synthesis of EPO 114-166 glycopeptide (1), presenting the O-linked glycophorin of erythropoietin, is described.",

author = "Jiehao Chen and Gong Chen and Bin Wu and Qian Wan and Zhongping Tan and Zihao Hua and Danishefsky, \{Samuel J.\}",

note = "Funding Information: This work was supported by the NIH (CA28824 to SJD). We thank Dr. George Sukenick, Ms. Sylvi Rusli, and Ms. Hui Fang of the Sloan-Kettering Institute{\textquoteright}s NMR core facility for mass spectral and NMR spectroscopic analysis (SKI core Grant No. CA02848). Postdoctoral fellowship support is gratefully acknowledged by BW (New York State Department of Health, New York State Breast Cancer Research and Education Fund). ",

year = "2006",

month = nov,

day = "13",

doi = "10.1016/j.tetlet.2006.09.045",

language = "English (US)",

volume = "47",

pages = "8013--8016",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "46",

}

TY - JOUR

T1 - Mature homogeneous erythropoietin-level building blocks by chemical synthesis

T2 - the EPO 114-166 glycopeptide domain, presenting the O-linked glycophorin

AU - Chen, Jiehao

AU - Chen, Gong

AU - Wu, Bin

AU - Wan, Qian

AU - Tan, Zhongping

AU - Hua, Zihao

AU - Danishefsky, Samuel J.

N1 - Funding Information: This work was supported by the NIH (CA28824 to SJD). We thank Dr. George Sukenick, Ms. Sylvi Rusli, and Ms. Hui Fang of the Sloan-Kettering Institute’s NMR core facility for mass spectral and NMR spectroscopic analysis (SKI core Grant No. CA02848). Postdoctoral fellowship support is gratefully acknowledged by BW (New York State Department of Health, New York State Breast Cancer Research and Education Fund).

PY - 2006/11/13

Y1 - 2006/11/13

N2 - A synthesis of EPO 114-166 glycopeptide (1), presenting the O-linked glycophorin of erythropoietin, is described.

AB - A synthesis of EPO 114-166 glycopeptide (1), presenting the O-linked glycophorin of erythropoietin, is described.

UR - https://www.scopus.com/pages/publications/33749507176

UR - https://www.scopus.com/pages/publications/33749507176#tab=citedBy

U2 - 10.1016/j.tetlet.2006.09.045

DO - 10.1016/j.tetlet.2006.09.045

M3 - Article

AN - SCOPUS:33749507176

SN - 0040-4039

VL - 47

SP - 8013

EP - 8016

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 46

ER -

Mature homogeneous erythropoietin-level building blocks by chemical synthesis: the EPO 114-166 glycopeptide domain, presenting the O-linked glycophorin

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this