@article{da95d2f4d6ea4a09b2c4ba42f4b7e937,
title = "Mechanism of the inverse-electron demand Diels-Alder reaction of 2-aminopyrroles with 1,3,5-triazines: detection of an intermediate and effect of added base and acid",
abstract = "In base, a 2-aminopyrrole reacted with a 1,3,5-triazine to give a zwitterion (Meisenheimer complex). Acid promoted its conversion to the pyrrolo[2,3-d]pyrimidine. A cascade mechanism with reversible steps is proposed to explain why both a base and an acid are needed for the cycloaddition to occur.",
author = "{De Rosa}, Michael and David Arnold",
note = "Funding Information: This work was supported by a Grant (CHE-0110801) from the National Science Foundation. We thank Dr. J. Honovich (Drexel University) for mass spectra and Dr. Alan Benesi (Penn State) for 19 F NMR spectra. X-ray crystallography was supported by the NSF Grant CHE-0131112 and carried out by Dr. Hemant Yennawar (Penn State). ",
year = "2007",
month = apr,
day = "23",
doi = "10.1016/j.tetlet.2007.03.012",
language = "English (US)",
volume = "48",
pages = "2975--2977",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd",
number = "17",
}