Abstract
Erythropoietin (Epo) induces a dose-dependent increase in intracellular free calcium concentration ([Ca1]) in single human BFU-E derived erythroblasts, which is specific for stage of differentiation and mediated through a voltage-independent ion channel permeable to calcium. This minireview examines the regulation of calcium channels by Epo during normal erythroid differentiation, as a model to delineate the immediate signaling events which follow interaction of Epo with its receptor.
Original language | English (US) |
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Pages (from-to) | 263-267 |
Number of pages | 5 |
Journal | Proceedings of the Society for Experimental Biology and Medicine |
Volume | 206 |
Issue number | 3 |
DOIs | |
State | Published - Jul 1994 |
All Science Journal Classification (ASJC) codes
- General Biochemistry, Genetics and Molecular Biology